Side Effects of Lyme

Flulike Symptoms

About 10 days after the tick bite, according to the National Institute of Neurological Disorders and Stroke, and after the rash has begun, flulike symptoms will occur. This includes fever, chills, headache, fatigue and muscle aches.


Lyme disease can trigger inflammation of the membranes surrounding the brain, known as the meninges. This is a condition known as meningitis which can cause symptoms such as fever, stiff neck and severe headache. The inflammation around the brain can interfere with the nerves resulting in a variety of conditions. Bell's palsy, temporary paralysis of the facial muscles, is one neurological effect. Other neurological effects include visual disturbances, irritability, decreased concentration, inhibition of memory and sleep disorders. Nerve damage can also occur in the arms or legs resulting in numbness or a tingling sensation in the hands or feet.

According to the American Academy of Family Physicians website, some symptoms of the neurological damage done by Lyme disease may include mood swings, difficulty remembering things or concentrating, a loss of memory and muscle weakness. The University of Maryland Medical Center warns that meningitis, poor motor coordination and Bell's palsy, a temporary paralysis of facial muscles, may also occur. Signs that meningitis might have taken hold in the brain include headaches and neck stiffness.

Heart Problems

Fewer than 10 percent of infected people develop heart problems, according to the University of Maryland Medical Center. Heart problems associated with Lyme disease include irregularities in heart rhythm, including heart palpitations or a slowing of the heart rate. Less obvious symptoms of heart issues caused by Lyme disease include lightheadedness, shortness of breath and fainting. Chest pain may also occur in some individuals.


A specific type of arthritis named Lyme arthritis may develop in some individuals exposed to Lyme disease, explains The arthritis from Lyme disease often strikes the knees and arthritic attacks can last up to a few months at a time. During an attack, joints may feel painful and start to swell. Antibiotics may be used to treat chronic Lyme disease that presents with arthritis symptoms. Pain medication, especially non-steroidal anti-inflammatory drugs, and siphoning fluid from swollen joints can help ease sore, arthritic joints. According to the University of Maryland Medical Center, approximately 60 percent of untreated people with Lyme disease will go on to develop arthritis and for 10 to 20 percent, the arthritis will be chronic.

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